Work Package 4

(1) To develop a protocol for drug screening in a 3D tissue model using nonlinear microscopy.

(2) To track nanoparticle endocytosis and endosomal escape at the single particle level to reveal receptor-mediated transport pathways for therapeutic delivery 

(3) To investigate the water behaviour inside fuel cell membrane for sustainable energy conversion

• Nonlinear microscopy images of cells grown on protein engineered scaffolds
• Resonant Four-wave mixing microscopy of gold nanoparticles in cells correlative with fluorescence microscopy